Modeling of Chronic Myeloid Leukemia: An Overview of In Vivo Murine and Human Xenograft Models

Figure 1

CML human and murine models till date. This figure summarizes established models for CML using chimeric mouse strains as well as different immunocompromised strains. Different experimental approaches and strategies along the time are also highlighted. “” refers to generation of serially transplantable leukemia and reference numbers (as indicated in Table 1) are denoted for each mouse model.