Intracoronary Infusion of Autologous CD133⁺ Cells in Myocardial Infarction and Tracing by Tc99m MIBI Scintigraphy of the Heart Areas Involved in Cell Homing

Table 4

Scintigraphic investigations of heart in (A) in responders (5 out of 8 patients) and (B) in nonresponders (3 out of 8 patients) before treatment and after a period of 9 months. Inclusion of Tc99 in the regions of anteroseptal, inferoseptal, and apex before and after cell therapy (stress condition) increased significantly only in inferoseptal region (𝑃=0.016) in responder patients. In nonresponders, inclusion of Tc99 in different regions of the heart was not significantly different between preoperative and postoperative perfusions under stress conditions.

(A)	Before treatment	After treatment	𝑃 value
Anteroseptal	56,60 ± 12,12	68,40 ± 14,55	0,194
Inferoseptal	51,60 ± 6,11	65,00 ± 7,75	0,016
Apex	51,80 ± 8,64	62,10 ± 9,71	0,106
(B)	Before treatment	After treatment	𝑃 value
Anteroseptal	71,33 ± 10,60	65,00 ± 6,7	0,510
Inferoseptal	50,33 ± 15,50	50,33 ± 12,0	1,00
Apex	49,67 ± 5,69	54,60 ± 12,6	0,566