Schizophrenia Research and Treatment / 2012 / Article / Tab 1

Review Article

Oral versus Long-Acting Injectable Antipsychotics in the Treatment of Schizophrenia and Special Populations at Risk for Treatment Nonadherence: A Systematic Review

Table 1

Characteristics of some older and newer LAIs [12, 17, 19].

VehiclePreparationDosing intervalInjection site pain/reactionsComments

FlupenthixolEster (decanoate)Viscoleo2–4 w+ + +[20, 21]
FluphenazineEster (decanoate)Sesame seed oil2–5 w+ + +[20, 21]
HaloperidolEster (decanoate)Sesame seed oil4 w+ + +[2022]
ZuclopenthixolEster (decanoate)Viscoleo2–4 w+ + + +[20, 21]
PaliperidoneEster (palmitate)Water (nanosuspension)4 w+ +[23]Metabolite of risperidone
OlanzapineSalt (pamoate)Water (microcrystalline suspension)2–4 w+ +[24, 25]Monitoring required for at least three hours due to small risk of IAIV
RisperidoneMicrospheresWater2 w+[23, 26, 27]Refrigeration required

IAIV: inadvertent intravascular injection; +: minimal; + +: low; + + +: moderate; + + + +: high.

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