Research Article
Relationships between Brain Structure and Metabolic Changes in Schizophrenia Patients Treated with Olanzapine: A Voxel-Based Morphometric Study
Table 4
Correlations between grey matter volumes and fasting leptin levels changes observed in schizophrenia patients after olanzapine treatment.
| |
R/L | Regions based on AAL atlas | MNI Coordinates |
Voxels | Z-Score | P value | | X | Y | Z |
| Positive correlations Leptin Change and Brain Structures | L | Angular | −27 | −56 | 35 | 100 |
2.06 | .020 | L | Precentral | −47 | 3 | 43 | 507 |
2.01 | .022 | R | Superior Frontal | 18 | 0 | 66 | 152 |
1.80 | .036 | R | Precentral | 49 | 3 | 26 | 29 |
1.75 | .040 |
| Negative correlations Leptin Change and Brain Structures | R | Middle Frontal | 36 | 21 | 23 | 1459 |
2.42 | .008 | R | Precuneus | 9 | −52 | 72 | 1682 |
2.27 | .011 | R | Hippocampus | 41 | −21 | −15 | 5796 |
2.11 | .018 | L | Precuneus | −10 | −42 | 69 | 244 |
1.76 | .039 |
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AAL: Automated Anatomical Labelling; MNI: Montreal Neurological Institute.
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