Relationships between Brain Structure and Metabolic Changes in Schizophrenia Patients Treated with Olanzapine: A Voxel-Based Morphometric Study

Table 4

Correlations between grey matter volumes and fasting leptin levels changes observed in schizophrenia patients after olanzapine treatment.

	R/L	Regions based on AAL atlas	MNI Coordinates			Voxels	Z-Score	P value
			X	Y	Z
Positive correlations Leptin Change and Brain Structures	L	Angular	−27	−56	35	100	2.06	.020
	L	Precentral	−47	3	43	507	2.01	.022
	R	Superior Frontal	18	0	66	152	1.80	.036
	R	Precentral	49	3	26	29	1.75	.040
Negative correlations Leptin Change and Brain Structures	R	Middle Frontal	36	21	23	1459	2.42	.008
	R	Precuneus	9	−52	72	1682	2.27	.011
	R	Hippocampus	41	−21	−15	5796	2.11	.018
	L	Precuneus	−10	−42	69	244	1.76	.039

AAL: Automated Anatomical Labelling; MNI: Montreal Neurological Institute.