Relationships between Brain Structure and Metabolic Changes in Schizophrenia Patients Treated with Olanzapine: A Voxel-Based Morphometric Study

Table 2

Correlations between grey matter volumes after olanzapine treatment and body weight changes observed in schizophrenia patients.

	R/L	Regions based on AAL atlas	MNI Coordinates			Voxels	Z-Score	P value
			X	Y	Z
Positive correlations; Body Weight Change and Brain Structures	R	Superior parietal	37	−50	59	1302	2.85	.002
	R	Inferior frontal operculum	50	8	18	1852	2.40	.008
Negative correlations; Body Weight Change and Brain Structures	L	Post-central	−52	−11	24	7107	3.32	.0001
	L	Hippocampus	−33	−20	−13	1387	1.99	.023
	R	Post-central	45	−15	34	3501	2.38	.009
	L	Precuneus	−14	−39	69	559	2.11	.018
	L	Thalamus	−7	−23	15	179	1.96	.025
	R	Precuneus	10	−59	43	19	1.68	.048