Review Article

AFM and FluidFM Technologies: Recent Applications in Molecular and Cellular Biology

Figure 4

Schematic representation of FluidFM technology. This setup includes a microchanneled cantilever fixed, in a watertight way, to a drilled AFM probe-holder; overpressure can be applied in the nanofluidic channel allowing the delivery of dyes, bioactive molecules, and microorganisms through an aperture in the pyramidal AFM tip. Moreover, the solution contained into the microchannel circuit can also be used to perform electrophysiological experiments. Reprinted with permission from [6], copyright 2009 American Chemical Society.