STAT3 Regulates Proliferation and Immunogenicity of the Ewing Family of Tumors In Vitro
Phosphorylated STAT3 is present in Ewing’s cell lines, but not PC3, which can be diminished by S3i-201 and reduces viability in ESFT cell lines. (a) Western blot analysis; Lysates from IL-6-stimulated and -unstimulated HeLa cells served as positive controls for P-STAT3 and total STAT3, respectively. The GADPH band is representative of loading in each lane. Data are representative of at least three independent experiments per cell line. (b) Cell viability is determined by MTT assay. Data are representative of at least three independent experiments per cell line.
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