Review Article

Unipolar Mania: Recent Updates and Review of the Literature

Table 1

(a) Retrospective studies related to prevalence of UM. (b) Prospective studies related to prevalence of UM.
(a)

Author (year)PrevalenceDefinition

Perris (1966) [12]4.5% among all BD patientsM ≥ 1, D = 0

Abrams and Taylor (1974) [13]28% of BD I patientsM-number not defined, D = 0

Nurnberger et al. (1979) [18]15.7% of BD I patientsM ≥ 1 hospitalization, D = no hospitalization or somatic treatment

Abrams et al. (1979) [14]18% of BD patientsM ≥ 2, D = 0

Perris (1982) [10]1.1% of BD patientsM ≥ 1, D = 0

Pfohl et al. (1982) [15]35.2% of hospitalized BD patientsM ≥ 1, D = 0

Rao et al. (1982) [16]2.7% of lithium clinic patientsOnly M during follow-up, D = 0

Venkoba Rao and Madhavan (1983) [17]12% of BD patients
(age of onset >60 years)
Only M during follow-up, D = 0

Srinivasan et al. (1982) [19]40% of hospitalized BD patientsM ≥ 3, D = 0

Margoob and Dutta (1988) [40]42% of all BD patientsM = not defined, D = not defined

Khanna et al. (1992) [20]44% of hospitalized BD patientsM ≥ 4, D = 0

Avasthi et al. (1996) [21]6.45% of all affective disordersM ≥ 3, D = 0

Aghanwa (2001) [22]47.2% of all BD patientsM ≥ 3 (includes hypomania as well) and affective illness for at least 4 years, D = 0

Yazici et al. (2002) [23]16.3% of BD I patientsM ≥ 4 and at least 4 years of follow-up, D = 0

Perugi et al. (2007) [25]21.8% of hospitalized BD I patientsM ≥ 3 and affective illness of at least 10 years, D = 0

D: depressive episode; M: manic episode.
(b)

Author (year)Duration of follow-upPrevalenceDefinition

Makanjoula (1985) [26]Five years53% of manic patientsM ≥ 2, D = 0

Solomon et al. (2003) [30]20 years27 subjects had the diagnosis of unipolar mania at the time of entry. Seven of these did not suffer any depressive episodes during the 15- to 20-year follow-up.Onset with M/HypoM, D = 0 for entire follow-up period

Dakhlaoui et al. (2008) [11]Five years65.3% of all bipolar I patientsM ≥ 2 and at least 5 years of follow-up, D = 0

D: depressive episode; M: manic episode; HypoM: hypomania.