Review Article

Effectiveness of Acupuncture for Lateral Epicondylitis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Table 3

GRADE analyses: acupuncture treatment for lateral epicondylitis.

Primary and secondary outcomesNo. of study (subjects)Risk of biasInconsistenceIndirectnessImprecisionPublication biasOverall quality of evidencea

Clinical efficacy rate8 (701)NoSeriousbNoNoNo+/+/+/−/; moderate
VAS6 (368)NoSeriousbNoSeriouscNo+/+/−/−/; low

GRADE = Grading of Recommendations Assessment, Development, and Evaluation; VAS = visual analogue scale. aGRADE working group grades of evidence: high quality = further research is very unlikely to change our confidence in the estimate of effect; moderate quality = further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate; low quality = further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate; very low quality = we are very uncertain about the estimate. bMeta-analytic results presented a serious inconsistency when I2 values were greater than 20% in the Q statistics. CMeta-analytic results presented a serious imprecision when 95% CI = effect size in the Q statistics.