| | | Author, year | Cases T/C | Diagnostic standard | Age (years) range, mean | Sex male/female |
| | OATCM | Wang Zhenhua, 2018 | 53/53 | GDTO and GPCRNDTCM | T: 41–72, 50.17 | C: 43–74, 51.49 | T:29/24 | C: 31/22 | | Kuang Yao, 2018 | 49/42 | GDTO and DTSTCM95D22S | T: 56.13 | C: 55.65 | T: 25/24 | C: 20/22 | | Wen Yangyang, 2019 | 63/63 | GDTO and GPCRNDTCM | T: 61.98 | C: 62.61 | T: 32/31 | C: 36/27 | | Cui Hongfang, 2018 | 61/61 | GDTO and GPCRNDTCM | T: 45–76, 64.7 | C: 46–75, 62.5 | T:31/31 | C: 32/29 | | Zheng Tao, 2019 | 50/50 | GDTO and CDTEDSTCM | T: 52–67, 63.26 | C: 51–67 | T:27/23 | C: 24/26 | | Yuan Fang, 2018 | 30/30 | GDTO (2007) and CDTEDSTCM | T: 42–72, 54.47 | C: 41–72, 60.63 | T: 4/26 | C: 6/24 | | Li Zhimin, 2018 | 48/48 | DCKO and CDTEDSTCM | T: 47–78, 57.42 | C: 45–76, 58.24 | T: 29/19 | C: 31/17 | | Liu Sheng, 2019 | 50/50 | GDTO (2010) and TCMDTS95D22S | T: 54–70, 58.34 | C:53–71, 57.43 | T: 25/25 | C: 26/24 | | Li Ping, 2019 | 74/74 | CETCMDTKO | T: 47–73, 60.69 | C: 45–75, 59.48 | T: 24/50 | C: 25/49 | | Li Linzhong, 2014 | 40/40 | NR | T: 42–75, 57.43 | C:41–74, 56.31 | 32/48 | — |
| | EUTCM | Yu Ming, 2018 | 73/73 | DCKO (2007) | 43–80, 54.86 | — | T: 40/33 | C: 46/27 | | Li Meng, 2017 | 30/30 | DCKO | T: 41–61, 52.41 | C: 42–60, 51.27 | T: 13/17 | C: 12/18 | | Lei Shoubin, 2014 | 49/49 | GDTO | T: 43–70, 57.5 | C: 44–71, 58.7 | T: 17/32 | C: 18/31 | | Zeng Jiaofei, 2014 | 50/50 | DCKO and K–L | T:45–63, 56.1 | C:45–65, 55.6 | T: 21/29 | C: 23/27 | | He Junlei, 2016 | 57/55 | DCKO | T: 45–73, 58.61 | C: 43–75, 59.06 | T: 16/41 | C:19/36 | | Chen Xi, 2015 | 40/40 | DCKO and GDTO | 40–75, 61.2 | — | 35/45 | — | | Liu Enxiong, 2016 | 68/68 | GDTO and GPCRNDTCM | T: 53–79, 61.29 | C: 51–78, 61.01 | T: 45/23 | C: 48/20 | | Zhou Gang, 2018 | 38/38 | GDTO (2007) and CDTEDSTCM | T: 46–70, 55.62 | C: 45–68, 54.33 | T: 16/22 | C: 20/18 | | Lui Gui, 2017 | 60/60 | GDTO and GPCRNDTCM | T: 59–72, 64.14 | C: 58–74, 64.29 | T: 19/41 | C: 21/39 | | Ding Liming, 2016 | 51/47 | NR | T: 63.00 | C: 67.08 | T: 16/35 | C: 14/33 | | Zhang Yanzhen, 2018 | 34/34 | CDTEDSTCM and DCKO (1995) | T: 42–73, 52.34 | C: 42–73, 54.24 | T: 12/22 | C: 10/24 | | Liu Yongyu, 2014 | 30/30 | DGDTO | T: 51–69 | C: 51–69 | NR | NR | | Wang Yuan, 2018 | 30/30 | DCKO (1995) | T: 40–74, 58.67 | C:44–73, 58.03 | T: 8/22 | C: 2/28 | | Zhang Zhi, 2018 | 52/51 | GDTO (2007) and K–L | T: 55–68, 63.9 | C: 53–70, 64.8 | T: 24/28 | C: 24/27 | | Chen Hongmei, 2017 | 31/30 | DCKO | T: 58.18 | C:55.90 | T: 13/18 | C: 11/19 | | Zhang Hui, 2016 | 51/51 | PO and TCMDTS95D22S | T: 41–79, 57.2 | C: 40–78, 56.1 | T: 17/34 | C:19/32 | | Liu Lin, 2018 | 40/40 | DCCASTCM | T: 40–70 | C: 40–70 | NR | NR | | Cui Shuping, 2016 | 35/35 | GDTO and GPCRNDTCM | T: 42–78 | C: 46–80 | T: 14/21 | C: 12/20 | | Wang Tao, 2017 | 30/30 | GPCRNDTCM and GDTO &TCMDTS95D22S | T: 42–57, 51.1 | C: 43–56, 50.2 | T: 8/22 | C: 9/21 | | Guo Wenhui, 2018 | 45/45 | DCKA (2007) | T: 73.4 | C: 72.7 | T: 25/20 | C: 21/24 |
| | ACU | Chen Juan, 2017 | 46/46 | GDTO (2007) and GPCRNDTCM | T: 45–76, 58.51 | C: 47–80, 59.23 | T: 25/21 | C: 27/19 | | Deng Jingming, 2015 | 40/40 | GDTO (2007) | T: 60.0 | C: 62.0 | T: 17/23 | C: 15/25 | | Ding Minghui, 2009 | 30/30 | DCKO (1986) | T: 59.37 | C: 58.93 | T: 8/22 | C:8/22 | | Guo Qian, 2019 | 79/79 | GDTO and DCTETCMKO | T: 45–78, 56.06 | C:45–78, 56.06 | T: 38/41 | C: 38/41 | | Li Jianwu, 2008 | 30/30 | DCKO (1995) | T: 53.0 | C: 55.6 | T: 11/19 | C:9/21 | | Li Jiangming, 2016 | 47/60 | NR | T: 65.12 | C: 64.26 | T: 5/42 | C: 7/53 | | Liang Chao, 2016 | 30/30 | GDTO (2007) | T: 61.4 | C: 60.3 | T: 22/8 | C: 21/9 | | Lin Ruyi, 2019 | 43/43 | GDTO (2007) | T: 40–69, 60.05 | C:40–69, 59.52 | T: 22/21 | C: 24/19 | | Liu Jin, 2014 | 30/30 | GDTO (2007) | T: 60.8 | C: 62.5 | T: 12/18 | C: 13/17 | | Luo Falan, 2018 | 42/42 | GDTO (2007) and GPCRNDTCM | T: 49–67, 59.27 | C: 51–68, 58.45 | T: 18/24 | C: 19/23 | | Wang Lina, 2018 | 59/59 | NR | T: 40–75, 52.13 | C: 41–77, 53.47 | T: 24/35 | C: 25/34 | | Wang Xiaoling, 2017 | 25/21 | DCKO (1995) | T: 50–74, 61 | C: 44–75, 58 | T: 8/17 | C:2/19 | | Xu Chen, 2018 | 45/41 | DCKO (1995) | T: 61.0 | C: 61.0 | T: 24/21 | C: 25/16 | | Xu Yahong, 2016 | 54/54 | GDTO and GPCRNDTCM | T: 45–73, 54.3 | C: 45–75, 55.2 | T: 25/29 | C:24/30 |
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C, control group; CDTEDSTCM, criteria for diagnosis and therapeutic effect of diseases and syndromes of traditional Chinese medicine; DCKO, diagnostic criteria of knee osteoarthritis; DTSTCM95D22S, diagnosis and treatment scheme of traditional Chinese medicine for 95 diseases in 22 specialties; DCTETCMKO, diagnostic criteria of therapeutic effect of traditional Chinese medicine on knee osteoarthritis; GDTO, guidelines for the diagnosis and treatment of osteoarthritis; GPCRNDTCM, guiding principles for clinical research of new drugs of traditional Chinese medicine; K–L, Kellgren–Lawwrence grading standard; NR, no report; PO, practical orthopaedics; T, trial group.
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