Research Article

Abnormal Circadian Modification of Aδ-Fiber Pathway Excitability in Idiopathic Restless Legs Syndrome

Table 4

Neurophysiological data.

FootNight vs dayHandNight vs day
NightDayNightDay

N1 latency (ms)RLS149.5 ± 32.8165.2 ± 34.2U test: 37.5
151.7 ± 36.6155.7 ± 31.8U test: 54
CTR172.4 ± 30.0174.1 ± 30.0U test: 51
143.6 ± 24152.3 ± 33.2U test: 46

RLS vs. CTRU test: 29
U test: 45
U test: 67.5
U test: 71

N1 amplitude (μV)RLS3.1 ± 1.12.7 ± 2.4U test: 73.5
3.8 ± 2.63.6 ± 2U test: 54
CTR3.7 ± 1.54.8 ± 2.0U test: 31.5
4.5 ± 2.75.2 ± 1.5U test: 43

RLS vs. CTRU test: 41
U test: 21
U test: 48
U test: 34

N2 latency (ms)RLS226.7 ± 46.8238.9 ± 54.4U test: 50
218.8 ± 54.4234.2 ± 56.4U test: 59
CTR236.8 ± 26.0223.2 ± 33.1U test: 62
201.8 ± 31.2197.5 ± 36.5U test: 67

RLS vs. CTRU test: 57
U test: 66
U test: 78
U test: 86

P2 latency (ms)RLS396.6 ± 83.4372.7 ± 60.9U test: 79
351.8 ± 60.4365.8 ± 72.6U test: 84
CTR364.8 ± 29.9353.2 ± 31.0U Test: 71.5
318.8 ± 37.9322.4 ± 41.7U Test:56.5

RLS vs. CTRU test: 79
U test: 75.5
U test: 84
U test: 83

N2-P2 amplitude (μV)RLS13.6 ± 5.211.5 ± 4.0U Test: 74.5
10.7 ± 5.111.1 ± 4.7U test: 60
CRL12.4 ± 7.115 ± 9.0U test: 49
14.1 ± 8.616.9 ± 11.1U test: 52

RLS vs. CTRU test: 74
U test: 50
U test: 47
U test: 39