Aspartoacylase Deficiency in the White Matter of Human Immunodeficiency Virus Encephalitis: Novel Mechanism in Axonal Damage

<table>Western blot study of aspartoacylase protein in the brain of patients with HIVE. (a) Aspartoacylase protein was deficient in the brain of patients with HIVE compared to the control. (b) Density analysis of the band showed reduced amount of ASPA protein in the brain with HIVE compared to the control brain.  Two-tailed <svg height="10.325" id="M3" style="vertical-align:-0.0pt" version="1.1" viewbox="0 0 11.75 10.325" width="11.75" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,10.325)">
<g transform="translate(72,-63.74)">
<text transform="matrix(1,0,0,-1,-71.95,63.79)">
<tspan style="font-size: 12.50px; " x="0" y="0">𝑃</tspan>
</text>
</g>
</g>
</svg> value was 0.02.</table>

Pathology Research International

fig2

Figure 2

Figure 2: Aspartoacylase Deficiency in the White Matter of Human Immunodeficiency Virus Encephalitis: Novel Mechanism in Axonal Damage 