Review Article

Serrated Polyposis: An Enigmatic Model of Colorectal Cancer Predisposition

Table 1

Summary findings in serrated polyposis from publications reporting more than five cases (adapted from Buchanan et al., 2010) [11].

AuthorYearCases (n)Mean age at diagnosis (years)Number of polyps observed% with CRCFamily history of CRC

Kalady et al. [27]2011115622-multiple25%38%
Buchanan et al. [11]2010126495–15040%59%*
Boparai et al. [9]200977562–5335%NS
Carvajal-Carmona et al. [25]2007324611-multiple25%59%
Chow et al. [26]2006384420-multiple26%50%
Renaut et al. [61]2001285820-multiple29%39%
Yeoman et al. [17]200724615-multiple54%17%
Ferrández et al. [28]2004155315-multiple0%0%
Lage et al. [48]2004145819–10043%33%
Hyman et al. [43]2004136220-multiple54%38%
Rashid et al. [54]20001358multiple77%38%
Leggett et al. [24]2001125730–>10058%17%
Rubio et al. [23]200610616–15970%10%
Spjut and Estrada [56]1977953Multiple11%NS
Williams et al. [29]198073750–1500%14%
Torlakovic and Snover [7]199665750–10067%NS
Place and Simmang [53]199966050–10050%14%

NS: not specified or unknown.
*Genetics clinic series.