Role of PPARγ in the Differentiation and Function of Neurons

Figure 2

Activation of PPAR γ improves neuronal health. Several neurodegenerative diseases showed clear deficiencies in mitochondrial function, oxidative stress, and memory impairment. Activation of PPARγ by natural ligands or TZDs could prevent these neurodegenerative changes mainly improving mitochondrial function and increasing antioxidant capacity in neurons.