Modulation of Preactivation of PPAR-β on Memory and Learning Dysfunction and Inflammatory Response in the Hippocampus in Rats Exposed to Global Cerebral Ischemia/Reperfusion

Table 1

Effect of GW0742 on the exploring time of rats after GCIRI.

Group	Exploring times (s)
	Day 8	Day 9	Day 10	Day 11	Day 12
Sham group	159.70±7.41	121.62±8.18	75.48±9.52	40.09±5.82	20.67±4.5
Model group	169.74±6.87^∗∗	135.08±7.09^∗∗	93.05±8.97^∗∗	65.70±7.40^∗∗	38.05±7.28^∗∗
GW0742-20 group	170.57±5.74	131.35±7.24	88.86±7.38	60.47±6.88	34.28±5.09
GW0742-60 group	166.40±5.85	128.13±6.77^#	82.04±7.83^##	54.37±7.05^##	29.66±6.21^##
GW0742-180 group	163.69±6.40^#	125.46±6.35^##	78.31±6.87^##	48.67±5.65^##/▵	25.48±5.83^##/▵

Dates are expressed as mean ± SD (𝑛=12). **𝑃<0.01 compared with sham operation group; ^#𝑃<0.05, ^##𝑃<0.01 compared with model group; ^▵𝑃<0.05 compared with GW0742 20 group.