Modulation of Preactivation of PPAR-β on Memory and Learning Dysfunction and Inflammatory Response in the Hippocampus in Rats Exposed to Global Cerebral Ischemia/Reperfusion

Figure 4

GW0742 inhibits protein expression of PPAR-β in hippocampus of rats after GCIRI (𝑛=4). The relative protein level of PPAR-β was normalized to endogenous β-actin protein for each sample. 1: vehicle sham group, 2: vehicle model group, 3: GW0742 20 model group, 4: GW0742 60 model group, and 5: GW0742 180 model group. Dates are expressed as mean ± SD of four individual experiments. **𝑃<0.01 compared with vehicle sham group; ^#𝑃<0.05,  ^##𝑃<0.01 compared with vehicle model group; ^Δ𝑃<0.05 compared with GW0742 20 model group.