Modulation of Preactivation of PPAR-β on Memory and Learning Dysfunction and Inflammatory Response in the Hippocampus in Rats Exposed to Global Cerebral Ischemia/Reperfusion

Figure 1

PPAR-β agonist GW0742 improves the global cerebral IRI-induced cytomorphological change in the hippocampus. (a) Representative pictures of H&E stained CA1 sections on day 12 post-GCIRI shown at 400x magnification. Scale bars = 50 μm. (b) Group data showing the effect of GW0742 on the cell death rate. **𝑃<0.01 compared with vehicle sham group; ^#𝑃<0.05,   ^##𝑃<0.01 compared with the vehicle model group; ^Δ𝑃<0.05 compared with GW0742 20 model group; ^●𝑃<0.05 compared with GW0742 60 model group, (𝑛=3).

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