iNOS Inhibition Reduces Lung Mechanical Alterations and Remodeling Induced by Particulate Matter in Mice

Table 1

ROFA instillation-induced lung mechanics alterations: after both five (ROFA-5d) and fifteen instillations (ROFA-15d), mice presented an increase in the percentage of respiratory system resistance (%Rrs) and elastance (%Ers) as well as in lung tissue impedance (%Htis) and lung tissue resistance (%Gtis) compared to control that received only saline. p<0.05 compared to saline (SAL group).

GROUPS	%Rrs	%Ers	%Gtis	%Htis
SALINE	67.05±16.99	39.70±10.51	40.36±6.65	33.23±7.47
ROFA-5d	213.58±29.06	149.62±42.57	124.93±20.72	74.72±10.26
ROFA-15d	214.18±31.97	175.95±59.21	106.56±42.25	104.99±12.56