iNOS Inhibition Reduces Lung Mechanical Alterations and Remodeling Induced by Particulate Matter in Mice

Figure 6

Metalloproteinase 12 expression. This figure represents the mean and SEM values of MMP-12 expression in both peribronchiolar (a) and alveolar (b) wall. The ROFA instillations increased the number of MMP-12-positive cells and iNOS inhibition significantly reduced this response only in airways. p<0.05 compared with saline groups; p<0.05 compared with animals that received ROFA and vehicle treatment.

(a)

(b)