iNOS Inhibition Reduces Lung Mechanical Alterations and Remodeling Induced by Particulate Matter in Mice

Figure 2

Lung inflammation and nitric oxide synthase expression. This figure represents the mean and SEM values of macrophages, neutrophils, nNOS, and iNOS-positive cells in peribronchiolar (a) and alveolar (b) wall. The animals that received fifteen instillations of ROFA presented higher values of all cells, and 1400W reduced inflammation and iNOS-positive cells, not interfering with nNOS expression. p<0.05 compared with saline groups; #p<0.05 compared with animals that received ROFA and vehicle treatment.

(a)

(b)