iNOS Inhibition Reduces Lung Mechanical Alterations and Remodeling Induced by Particulate Matter in Mice

Figure 1

Lung mechanics. This figure represents the mean and SEM percentage of maximal increase of respiratory system resistance (Rrs) and elastance (Ers) relative to baseline. The animals that received fifteen instillations of ROFA presented higher values of both Rrs and Ers compared to control and 1400W treatment reduced this response. p<0.05 compared with saline groups; p<0.05 compared with animals that received ROFA and vehicle treatment.