Pulmonary Medicine / 2014 / Article / Tab 1 / Review Article
Effect of PAH Specific Therapy on Pulmonary Hemodynamics and Six-Minute Walk Distance in Portopulmonary Hypertension: A Systematic Review and Meta-Analysis Table 1 Underlying causes of portal hypertension in the included studies [
10 –
21 ].
1st author and year ALD HBV or HCV Cryptogenic ALD + HCV Miscellaneous Krowka 1999 14 1 1 3 3 1 HCC + HCV, 1 sarcoidosis, 2 PBC, 1 Budd Chiari, 1 AIH Hoeper 2005 11 7 1 0 2 1 biliary atresia Reichenberger 2006 14 7 3 3 PBC, 1 Budd Chiari Sussman 2006 8 4 1 2 1 Fix 2007 35 7 9 3 10 1 HIV, 2 HCC, 2 PBC, 1 AIH Hoeper 2007 (bosentan) 18 11 3 1 0 1 PVT, 2 AIH Hoeper 2007 (iloprost) 13 6 2 0 0 1 biliary duct atresia, 4 AIH
Gough and White 2009 11 4 2 0 4 1 ALD + NASH Hemnes 2009 13 1 8 0 0 1 PBC Melgosa 2010 13 2 7 0 0 1 hemochromatosis, 2 PBC, 1 portal vein thrombosis Halank 2011 13 8 1 3 0 1 PBC Hollatz 2012 11 5 1 0 3 1 ALD + NASH + PBC, 1 biliary atresia Savale 2013 34 20 4 3 6 PVT, 1 AIH Total 83 (40%) 43 (20%) 12 (5%) 26 (12%) 41 (20%)
ALD: alcoholic liver disease; HBV: hepatitis B; HCV: hepatitis C; HCC: hepatocellular cancer; PBC: primary biliary cirrhosis; AIH: autoimmune hepatitis; HIV: human immunodeficiency virus; PVT: portal vein thrombosis; NASH: nonalcoholic steatohepatitis.