Research Article

Risk of Dementia in Patients with Depression or Parkinson’s Disease: A Retrospective Cohort Study

Table 1

Clinical characteristics of study subjects.

Clinical characteristicsTotalWithout PDWith PD
(n = 6065)(n = 4852)(n = 1213)

Age, years (mean ± SD)62.8 ± 17.162.8 ± 17.162.9 ± 17.00.823
Gender1.000
 Female2925 (48.2)2340 (48.2)585 (48.2)
 Male3140 (51.8)2512 (51.8)628 (51.8)
CCI1.000
 03405 (56.1)2724 (56.1)681 (56.1)
 1-22055 (33.9)1644 (33.9)411 (33.9)
3605 (10.0)484 (10.0)121 (10.0)
Depression688 (11.3)356 (7.3)332 (27.4)<0.001
Hypertension2077 (34.2)1625 (33.5)452 (37.3)0.013
Diabetes mellitus915 (15.1)713 (14.7)202 (16.7)0.088
Hyperlipidemia807 (13.3)633 (13.0)174 (14.3)0.234
Ischemic heart disease800 (13.2)621 (12.8)179 (14.8)0.072

Note. PD = Parkinson’s disease, n = case number, SD = standard deviation, CCI = Charlson comorbidity index, and  =  value. Categorical data were presented as number (%); continuous data were expressed as mean ± standard deviation.