Deep Brain Stimulation of Hemiparkinsonian Rats with Unipolar and Bipolar Electrodes for up to 6 Weeks: Behavioral Testing of Freely Moving Animals

Figure 5

Short-term and long-term effects of DBS with uni- and bipolar electrodes on the apomorphine-induced rotation behavior of hemiparkinsonian rats. (a) and (b) refer to test groups and controls, respectively. Different column patterns indicate the different times of behavioral testing; black: 12–14 days after 6-OHDA or sham lesion; gray and hatched: after the durations of DBS or sham stimulation indicated in the group labels. For experimental details see Table 1. Significance levels are indicated with asterisks as follows: , b (borderline): according to one-way ANOVA. Asterisks refer to comparisons with corresponding black columns.

(a)

(b)