Predictors of Functional and Quality of Life Outcomes following Deep Brain Stimulation Surgery in Parkinson’s Disease Patients: Disease, Patient, and Surgical Factors

Table 1

Beta estimates for health status measures collected at 2 follow-ups.

		6 months postop.			1 year postop.
			Estimate (95% CI)	value		Estimate (95% CI)	value
UPDRS II	Age	39	−0.05 (−0.34, 0.23)	0.7058	32	0.03 (−0.3, 0.36)	0.8438
	Disease duration	38	−0.45 (−1.00, 0.11)	0.1127	31	0.21 (−0.56, 0.97)	0.5859
	BMI	37	0.49 (0.04, 0.94)	0.0332	32	0.68 (−0.002, 1.37)	0.0507
	Laterality (versus unilateral)
	Staged bilateral	39	1.16 (−4.58, 6.89)	0.6849	32	0.53 (−6.75, 7.82)	0.8819
	Simultaneous bilateral	39	−3.68 (−12.69, 5.32)	0.4118	32	−5.46 (−14.34, 3.42)	0.2179
	Electrode passes (right)	29	2.09 (−0.41, 4.60)	0.0978	24	1.96 (−1.77, 5.69)	0.2876
	Electrode passes (left)	35	−1.21 (−4.29, 1.87)	0.4300	30	−2.18 (−6.14, 1.78)	0.2681
	Electrode passes (total)	36	0.31 (−1.15, 1.76)	0.6731	30	0.00 (−1.96, 1.97)	0.9963
	% equivalent levodopa dose	37	1.83 (−3.93, 7.58)	0.5233	30	0.89 (−6.15, 7.94)	0.7967
	On UPDRS III	39	0.09 (−0.21, 0.38)	0.5535	31	0.22 (−0.10, 0.54)	0.1709
	Tremor	39	−0.95 (−5.78, 3.88)	0.6909	32	1.35 (−4.41, 7.12)	0.6345
	Dyskinesia	39	−2.46 (−7.28, 2.36)	0.3072	32	−2.06 (−7.86, 3.74)	0.4736
	Freezing	39	2.32 (−2.97, 7.62)	0.3792	32	3.85 (−2.55, 10.26)	0.2284
	Falls/balance	39	6.48 (1.11, 11.84)	0.0193	32	6.45 (−0.38, 13.28)	0.0634
	Marital status	38	−1.86 (−7.35, 3.63)	0.4958	31	2.74 (−3.88, 9.36)	0.4041
EQ-5D index	Age	45	0.00 (−0.01, 0.00)	0.3403	36	0.00 (−0.01, 0.01)	0.9897
	Disease duration	43	0.01 (0.00, 0.02)	0.1810	35	−0.01 (−0.02, 0.00)	0.0696
	BMI	45	0.001 (−0.009, 0.011)	0.8450	36	−0.002 (−0.014, 0.011)	0.7983
	Laterality (versus unilateral)
	Staged bilateral	44	0.08 (−0.02, 0.19)	0.1252	36	−0.01 (−0.14, 0.12)	0.9127
	Simultaneous bilateral	44	0.13 (−0.04, 0.29)	0.1351	36	0.003 (−0.15, 0.16)	0.9654
	Electrode passes (right)	33	−0.02 (−0.06, 0.02)	0.3494	28	−0.03 (−0.09, 0.04)	0.3837
	Electrode passes (left)	38	0.04 (−0.02, 0.11)	0.2006	32	0.07 (0.00, 0.14)	0.0508
	Electrode passes (total)	41	0.02 (−0.01, 0.05)	0.2458	34	0.01 (−0.03, 0.04)	0.6988
	Equivalent levodopa dose	42	−0.07 (−0.19, 0.04)	0.2000	34	0.06 (−0.06, 0.19)	0.3138
	On UPDRS III	44	−0.01 (−0.01, 0.00)	0.0050	35	0.00 (−0.01, 0.00)	0.6310
	Tremor	44	0.03 (−0.07, 0.13)	0.5516	36	0.07 (−0.03, 0.17)	0.1602
	Dyskinesia	44	−0.01 (−0.11, 0.09)	0.8448	36	0.02 (−0.09, 0.12)	0.7197
	Freezing	44	−0.03 (−0.13, 0.08)	0.5955	36	−0.09 (−0.19, 0.01)	0.0762
	Falls/balance	44	−0.06 (−0.17, 0.05)	0.269	36	−0.12 (−0.23, −0.02)	0.0191
	Marital status	44	−0.04 (−0.15, 0.08)	0.4992	35	−0.04 (−0.16, 0.07)	0.4668