A Case-Control Association Study of RANTES (-28C>G) Polymorphism as a Risk Factor for Parkinson’s Disease in Isparta, Turkey

Table 3

Five marker haplotype estimates and odds ratio (OR) analysis.

Haplotypes	IL-8	MCP-1	RANTES	CCR2	CCR5	Frequency	OR	p value
	(-251A/T)	(-2518A/G)	(-28C/G)	(V64I) (+190; G/A)	(-Δ32)		95% CI
1	A	A	C	G	N	0.429	1.00	—
2	T	A	C	G	N	0.317	0.66 (0.24–1.85)	0.43
3	T	G	C	A	N	0.141	0.08 (0.01–0.63)	0.019
4	T	G	C	G	N	0.065	0.58 (0.10–3.45)	0.55

Global haplotype association p value = 0.0001.
PD: Parkinson’s disease, OR: odds ratio, and CI: confidence interval.
The most common haplotype is the reference haplotype.
Data are presented as frequencies; p values < 0.05 are considered significant.