Research Article

Expansion of Lymphocytes from Prostatic Adenocarcinoma and Adjacent Nonmalignant Tissue

Table 1

Clinicopathological features.

Patient IDAge at surgeryPathological stageMargin statusGleason score1Other pathological featuresPSA level (preoperative or pre-ADT)PSA levels after surgeryPSA recurrencePSA at last follow-up2

Did not receive neoadjuvant androgen-deprivation therapy:
#0162T3b+7EPE, SV55.610.14Yes1.7
#0251T2c6PNI7.13<0.05No<0.05
#0365T1c+7PNI6.13<0.05Yes0.037
#0464T2c6PNI5.25<0.05No<0.05
#0562T27EPE, PNI3.16<0.05No<0.05
#0662T27PNI6.26<0.05No<0.05
#0766T27Nil17.6<0.04No<0.05
#0869T3b7PNI, EPE, SV24.640.27No0.24
#0964T3a7PNI, EPE10.07<0.05Yes0.12
#1050T3a+7PNI45.280.056Yes<0.05

Received neoadjuvant androgen-deprivation therapy:
#1159T2cn/aNiI5.38<0.05No<0.05
#1269T2cn/aPNI13.84<0.05Yes0.14
#1362T2cn/aPNI10.19<0.05No<0.05
#1449T3an/aPNI247.40.08Yes0.08
#1567T3b+n/aPNI, EPE, SV (bilat)33.88<0.05Yes<0.05

ADT, androgen-deprivation therapy; EPE, extraprostatic extension; PNI, perineural invasion; PSA, prostate-specific antigen; SVI, seminal vesicle involvement. Only malignant tissue was available; that is, matched nonmalignant tissue was not assessed. 1Gleason score not assessed (n/a) in those treated with neoadjuvant androgen-deprivation therapy. 2Median time to follow-up after surgery was 887 days.