High Serum Alkaline Phosphatase Flare after First-Line Androgen Deprivation Therapy Predicts Poor Prognosis in Metastatic Prostate Cancer Patients Treated with Second-Generation Androgen Receptor Targeted Therapy

Figure 3

Waterfall plot of the best PSA decline after CRPC treatment compared with an ALP flare ratio less than 1.57 and 1.57 or more in the group that received second-generation androgen receptor targeting therapy (ART) (a, b) and an ALP flare ratio less than 1.90 and 1.90 or more in the group that received docetaxel (c, d).

(a)

(b)

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(d)