Interleukin-10 Induces Expression of Neuroendocrine Markers and PDL1 in Prostate Cancer Cells

<div>Slight upregulation of EP4 in IL10, IL6, and ENZ treated LNCaP cells. (a) LNCaP, (b) 16D<sup>CRPC</sup>, (c) 46D<sup>ENZR</sup> resistant cells were stimulated with 100 ng/mL IL10, IL6, or ENZ for 7 days prior to lysate collection. Expression levels of EP4 were determined by immunoblotting of cell lysates. Data plotted represents EP4 band intensities normalized to GAPDH protein levels. Experiments were repeated 3 times. 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Prostate Cancer

fig4

Figure 4

Figure 4: Interleukin-10 Induces Expression of Neuroendocrine Markers and PDL1 in Prostate Cancer Cells 