Synthetic Apparent Diffusion Coefficient for High b-Value Diffusion-Weighted MRI in Prostate

Figure 2

Log-linear relationship between ADC and b-value. Example of log-linear model fit to targeted tissue of a 69-year-old patient with adenocarcinoma in peripheral zone (PZ) of prostate. Axial DWI images of b-1000 with regions of interest (ROIs) in PZ lesion (a), normal PZ (b), normal transition zone (c), and corresponding graphs with b-value (x-axis), ADC (y-axis), and log-linear fit for each ROI (d, e, and f). The plots (g), (h), and (i) show the log-linear model fit to ADC value at b-400, b-700, and b-1000 (black solid line) and extrapolation of sADC at b-1500 and b-2000(dotted line). Bottom row shows the sDWI, ADC, and sADC maps at b-2000 and color-coded error map of the corresponding slice.