CHEK2^∗1100delC Mutation and Risk of Prostate Cancer

Table 2

Characteristics and results of 7 excluded prostate cancer studies.

Carrier/Total	Population	Country	OR/HR (95% CI)	value	Ref.
14/1,864	Unselected cases	PL	3.5 (1.6–7.5)	0.002	[25, 26]
3/249	Familial cases		5.6 (1.6–19.9)	0.02
12/5,496	Controls		Reference
3/84	Cases	US	NA	NA	[27, 28]
	Families with breast cancer history	UK, NE, DE, US	2.68 (ratio of carrier RR versus noncarrier RR)	0.26	[29]
3/690	Unselected cases	PL	2.1 (0.5–9.4)	0.32	[30]
1/98	Familial cases		4.9 (0.5–44.6)	0.11
4/1,921	Controls		Reference
3/690	Unselected cases	PL	1.74 (0.48–6.35)	0.39	[31]
10/4,000	Controls		Reference

PL: Poland, UK: United Kingdom, NE: Netherlands, DE: Denmark, US: United States, NA: not available.