Review Article
CHEK2∗1100delC Mutation and Risk of Prostate Cancer
Table 1
Characteristics and results of 5 prostate cancer studies.
| Carrier/Total | Population | Country | OR/HR (95% CI) | value | Ref. |
| 21/3,750 | Unselected cases | PL | 3.2 (1.4–7.5) | 0.009 | [20] | 4/412 | Familial cases | | 5.5 (1.6–19.0) | 0.01 | | 7/3,956 | Controls | | Reference | | |
| 1/145 | Without family history | SW | 0.70 (0.07–6.78) | 0.76 | [21] | 4/254 | Familial cases | | 1.61 (0.36–7.27) | 0.53 | | 3/305 | Controls | | Reference | | |
| 7/537 | Unselected cases | FI | 3.14 (0.65–15.16) | 0.15 | [22] | 4/120 | Familial cases | | 8.24 (1.49–45.54) | 0.02 | | 2/480 | Controls | | Reference | | |
| 4/178 | Cases | US | NA | NA | [23] | 1/400 | Without family history | | NA | NA | | 1/298 | Familial cases | | NA | NA | | 0/423 | Controls | | NA | NA | |
| 2/114 | Cases | DE | 2.3 (0.6–9.5) | NA | [24] | 21/4,094 | Controls | | Reference | | |
| 36/5,124 | Unselected cases | Pooled | 1.98 (1.23–3.18) | 0.004 | Combined | 13/1,084 | Familial cases | | 3.39 (1.78–6.47) | 0.0001 | | 33/9,258 | Controls | | Reference | | |
|
|
PL: Poland, SW: Sweden, FI: Finland, US: United States, DE: Denmark, NA: not available.
|