Research Article

Role of p73 Dinucleotide Polymorphism in Prostate Cancer and p73 Protein Isoform Balance

Figure 1

Association between rs1801173 and overall survival (a) and prostate cancer specific survival (b). A role of p73 DNP in prostate cancer progression and aggressiveness was investigated. p73 DNP is marginally associated with overall death (dominant model, hazard ratio (HR) = 0.76, 95%CI = 0.57–1.00, by Cox regression adjusted for age) as well as PCa specific death (HR = 0.69, 95%CI = 0.45–1.06, by the competing risk regression adjusted for age).
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(a)
129582.fig.001b
(b)