Hepatoprotective Effects of Morinda citrifolia Leaf Extract on Ovariectomized Rats Fed with Thermoxidized Palm Oil Diet: Evidence at Histological and Ultrastructural Level

Figure 2

(a) Electron micrograph showing the hepatocyte of the Sham group. Normal organelles were seen. EM 6000x. (b) Electron micrograph showing the hepatocyte of the untreated OVX group. Massive amounts of lipid droplets (LD) accumulation (circle) were present around the relatively enlarged nucleus. EM 6000x. (c) Electron micrograph showing the hepatocyte of the OVX rats fed with TPO diet and treated with statin (OVX+ST). Lipid droplet (LD) accumulation was seen surrounding the nucleus. EM 6000x. (d) Electron micrograph showing the hepatocyte of the OVX rats fed with TPO diet and treated with MC leaf 500 mg/kg. Relatively less lipid droplets were observed. EM 6000s. (e) Electron micrograph showing the hepatocyte of the OVX rats fed with TPO diet and treated with MC leaf 1000 mg/kg (OVX+MCHD). Limited amounts of lipid droplets were present. EM 6000x.

(a)

(b)

(c)

(d)

(e)