Mitochondrial Oxidative Stress Impairs Energy Metabolism and Reduces Stress Resistance and Longevity of C. elegans

Figure 1

Heat-stress resistance and lifespan of C. elegans are reduced under paraquat exposure. (a) Survival at 37°C was assessed due to the penetration of SYTOX™ Green nucleic acid stain into dead cells. (b) Survival of wild-type C. elegans N2 at 20°C was assessed in the absence and presence of 5 mM paraquat. Log-rank (Mantel-Cox) test; , , and .

(a)

(b)