Research Article
Phosphocreatine Improves Cardiac Dysfunction by Normalizing Mitochondrial Respiratory Function through JAK2/STAT3 Signaling Pathway In Vivo and In Vitro
Figure 4
Effects of PCr on STZ-instigated apoptosis in DCM. (a) The TUNEL and DAPI recoloring on the myocardium. The nuclei of TUNEL-positive cells are shown utilizing green fluorescence. (b) Quantification of TUNEL-positive cells. (c) The protein dimensions of Bcl-2, Bax, caspase 3, caspase 9, cleaved caspase 3, cleaved caspase 9, and cytochrome c (mitochondria) were recognized by western blot in tissue homogenate. (d, e, f, g, h, i) Quantifications of western blot. Data are exhibited as the (). and vs. the control group. , , and vs. the STZ group.
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