Research Article

Differential Effects of Silibinin A on Mitochondrial Function in Neuronal PC12 and HepG2 Liver Cells

Table 2

Summary of the effects of silibinin on mitochondrial parameters in HepG2 and PC12 cells.

RespirationBasal MMP/+SNPBasal ATP/+SNPCitrate synthase activityGlycolysis

HepG2↑/↑↑↑/↑
PC12↔/↑↑↑/↑↑

↑ indicates an increase, ↓ indicates a reduction, and ↔ indicates no change. SNP = sodium nitroprusside.