Research Article

Sepiapterin Improves Vascular Reactivity and Insulin-Stimulated Glucose in Wistar Rats

Figure 4

(a–d). Mitochondrial respiration. Aorta from animals were permeabilized and exposed to two different experiments using various substrates (a, b: pyruvate, malate, glutamate, ADP, cytochrome c, succinate, oligomycin, and carbonyl cyanide-4-(trifluoromethoxy)phenylhydrazone (FCCP)) or (c, d: octanoylcarnitine, malate, glutamate, ADP, cytochrome c, succinate (S), oligomycin, and (FCCP)). State 2 respiration (S2), state 3 respiration (S3), and state 4 respiration (S4) were measured. States were analyzed as shown above, including respiratory control ratio (RCR, state 3(S)/state 4). Control group and SEP . Data are presented as , , Student’s -test.
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