Research Article

Stevia Prevents Acute and Chronic Liver Injury Induced by Carbon Tetrachloride by Blocking Oxidative Stress through Nrf2 Upregulation

Figure 5

Stevia prevents the expression of proinflammatory cytokines in chronic liver damage. Protein levels of TNF-α (a), IL-1β (b), IL-6 (c), and IL-10 (d) in samples of liver tissue were determined by Western blot analysis of the control, CCl4-, CCl4 + stevia-, and stevia-treated rats. β-actin was used as a control. The values are expressed as the fold increase of OD normalized to the control group values (control = 1). Each bar represents the mean value of three rats ± SE (). versus the control group; versus the CCl4 group.
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