Research Article

Stevia Prevents Acute and Chronic Liver Injury Induced by Carbon Tetrachloride by Blocking Oxidative Stress through Nrf2 Upregulation

Figure 4

Stevia prevents the activation of the proinflammatory factor NF-κB (p65) in chronic liver damage. Representative p65 immunohistochemistry of liver slices from control (a), CCl4- (b), CCl4 + stevia- (c), and stevia- (d) treated rats. (e) depicts the percentage of positivity of p65 obtained from immunohistochemistry slices. (f) depicts the protein levels in the samples of liver tissue determined by Western blot analysis. The values are expressed as the fold increase of OD normalized to the control group values (control = 1). Each bar represents the mean value of three rats ± SE (). versus the control group; versus the CCl4 group.
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