Research Article
Stevia Prevents Acute and Chronic Liver Injury Induced by Carbon Tetrachloride by Blocking Oxidative Stress through Nrf2 Upregulation
Figure 2
Stevia prevents chronic liver inflammation, necrosis, and cholestasis in chronic liver damage. The representative hematoxylin and eosin staining of liver sections obtained from the control (a), CCl4 (b), CCl4 + stevia (c), and stevia-treated rats (d). Histograms depict the liver (e), body (f), and body : liver weight ratio (g), alanine aminotransferase (ALT) (h), alkaline phosphatase (AP) (i), and gamma-glutamyl transpeptidase (γ-GTP) (j) serum activities, and liver glycogen content (k), total (l), and unconjugated serum bilirubin (m) levels. Each bar represents the mean value of experiments performed in duplicate ± SE (). versus the control group; versus the CCl4 group.
(a) |
(b) |
(c) |
(d) |
(e) |
(f) |
(g) |
(h) |
(i) |
(j) |
(k) |
(l) |
(m) |