Research Article

Honokiol Ameliorates Myocardial Ischemia/Reperfusion Injury in Type 1 Diabetic Rats by Reducing Oxidative Stress and Apoptosis through Activating the SIRT1-Nrf2 Signaling Pathway

Figure 3

EX527 blunted HKL-induced suppression on oxidative stress level in MI/R-injured diabetic myocardium. (a) Myocardial SOD contents. (b) Myocardial MDA contents. (c) Representative blots. (d) NQO-1 expression. (e) HO-1 expression. (f) gp91phox expression. (g) Representative images of DHE staining (300x, bar = 100 μm). (h) DHE intensity. Data are presented as the mean ± SEM ( in each group). versus the T1D + sham group, versus the T1D + MI/R group, versus the T1D + MI/R + HKL group.
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