Glycine Increases Insulin Sensitivity and Glutathione Biosynthesis and Protects against Oxidative Stress in a Model of Sucrose-Induced Insulin Resistance
Table 1
General characteristics of the animals.
Variables
C
CG
SF
SFG
Food intake (g/day/rat)
22.7 ± 0.8
19.3 ± 1.5
12.5 ± 0.7
10.7 ± 1.3
Water intake (mL/day/rat)
45.7 ± 2.7
46.5 ± 2.8
47.5 ± 2.9
44.5 ± 2.5
Energy intake (kcal/day/rat)
315.6 ± 8.5
305.5 ± 9.6
360.1 ± 8.4
356.7 ± 5.8
Body weight (g)
448 ± 12
467 ± 15
475 ± 10
466 ± 9
Intra-abdominal fat (g)
6.4 ± 1.4
6.3 ± 1.9
23.4 ± 1.8
9.8 ± 1.9
Plasma TG (mg/dL)
43.1 ± 7.5
32.8 ± 4.3
96.9 ± 7.1
75.0 ± 7.0
Liver TG (μmol/mg)
77.5 ± 8.5
85 .5 ± 9.5
217.7 ± 28.4
155.7 ± 35.6
Plasma FFA (mM)
0.7 ± 0.07
0.5 ± 0.1
1.2 ± 0.1
0.7 ± 0.1
Liver FFA (μmol/mg)
78.5 ± 11.4
68.6 ± 2.5
117.5 ± 27.6
62.5 ± 31.7
Chol (mg/dL)
38.4 ± 12.8
47.9 ± 12.1
42.2 ± 13.2
55.1 ± 16.9
Glucose (mM)
6.0 ± 1.0
5.5 ± 0.7
5.9 ± 1.2
6.4 ± 1.5
Insulin (pΜ)
111.6 ± 23.4
119.9 ± 28.4
187.5 ± 36.5
122.9 ± 19.6
Chol (cholesterol), glucose, and insulin were determined in plasma. TG (triglycerides) and FFA (free fatty acids) were determined in both liver homogenate and plasma. Values represent mean ± SD, different animals. (C versus SF) and (SFG versus SF).