Glycine Increases Insulin Sensitivity and Glutathione Biosynthesis and Protects against Oxidative Stress in a Model of Sucrose-Induced Insulin Resistance

Figure 4

Representative Western blot and graph data (upper panels) depicting antioxidant protein abundance such as GPX1 (a), GPX3 (b), CAT (c), and Cu/Zn-SOD (d) in liver homogenate isolated from overnight-fasted C (control), SF (sucrose-fed), CG (control + glycine), and SFG (sucrose-fed + glycine) rats. Values in the panels correspond to the ratio OD of GPX1(a) or GPX3/OD of β-actin (b) and to the ratio OD of CAT/OD of β-actin (c) and to the ratio OD of CuZn-SOD/OD of β-actin (d). (e) Representative Western blot. Data are expressed as the mean ± SD ( different preparations from 4 different animals). compared to the control group; compared to the SF group.

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