Antiaging of Cucurbitane Glycosides from Fruits of Momordica charantia L.

Figure 5

Effects of compound 9 on SOD1 (a), SOD2 (b), UTH1 (c), and SKN7 (d) yeast gene expression. The gene levels of BY4741 yeast cells were tested after treated with compound 9 at 1 and 3 μM. Compound 9 significantly increased SOD1 and SOD2 yeast gene level at 12 h and inhibited UTH1 and SKN7 yeast gene expression at 24 h. Amounts of the mRNA above were normalized to that of TUB1. The results were displayed as mean ± SEM for three independent experiments (, , and , compared with the control group).

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