TY - JOUR A2 - Curcio, Manuela AU - Tressera-Rimbau, A. AU - Arranz, S. AU - Eder, M. AU - VallverdĂș-Queralt, A. PY - 2017 DA - 2017/10/24 TI - Dietary Polyphenols in the Prevention of Stroke SP - 7467962 VL - 2017 AB - Polyphenols have an important protective role against a number of diseases, such as atherosclerosis, brain dysfunction, stroke, cardiovascular diseases, and cancer. Cardiovascular diseases are the number one cause of death worldwide: more people die annually from cardiovascular diseases than from any other cause. The most important behavioural risk factors of heart disease and stroke are unhealthy diet, physical inactivity, tobacco use, and excess alcohol intake. The dietary consumption of polyphenols has shown to be inversely associated with morbidity and mortality by cardio- and cerebrovascular diseases. It is well-known that the protective effects of polyphenols in vivo depend on the grade how they are extracted from food and on their intestinal absorption, metabolism, and biological action with target tissues. The aim of this review was to summarise the relation between polyphenols of different plant sources and stroke in human intervention studies, animal models, and in vitro studies. SN - 1942-0900 UR - https://doi.org/10.1155/2017/7467962 DO - 10.1155/2017/7467962 JF - Oxidative Medicine and Cellular Longevity PB - Hindawi KW - ER -