Research Article

NRF2 Plays a Critical Role in Both Self and EGCG Protection against Diabetic Testicular Damage

Figure 4

NRF2 mediated EGCG prevention of diabetes-induced testicular ER stress. The status of ER stress was determined by measuring protein levels of (a) CHOP, (b) caspase12, (c) BIP, and (d) ATF4, using Western blot. The protein levels were normalized with GAPDH. Data were normalized as fold variation to Ctrl and were presented as means ± SD (). versus Ctrl; versus DM. ER: endoplasmic reticulum; CHOP: C/EBP homologous protein; BIP: binding immunoglobulin protein; ATF4: activating transcription factor 4; other abbreviations are the same as those in Figure 1.
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