NRF2 Plays a Critical Role in Both Self and EGCG Protection against Diabetic Testicular Damage

Figure 2

NRF2 was required for both self and EGCG protection against diabetes-induced testicular apoptotic cell death. (a) H&E staining was conducted for observation of morphological change. (b) Testicular apoptotic cell death was detected by TUNEL assay, from which (c) TUNEL⁺ cells were calculated. Data were presented as means ± SD (). versus Ctrl; ^† versus DM; ^‡ versus WT DM. H&E: hematoxylin and eosin; TUNEL: terminal deoxynucleotidyl transferase-mediated dUTP nick end labelling; ⁺: positive; other abbreviations are the same as those in Figure 1.

(a)

(b)

(c)