Periodic Exposure of Keratinocytes to Cold Physical Plasma: An In Vitro Model for Redox-Related Diseases of the Skin

Table 3

Expression (fold change compared to untreated control) of cytokines and growth factors with at least one significant modulation throughout the time course of plasma treatment.

Gene name	Gene ID	w2	w6	w8	w10	w12
Interleukin-1α	IL1A	11.85	17.09	4.01	1.36	3.18
Interleukin-1β	IL1B	4.30	5.65	2.30	−1.01	2.14
Interleukin-4	IL4	5.72	−1.34	1.05	−1.33	−1.77
Interleukin-5	IL5	5.51	−1.06	−2.05	−2.34	−1.92
Interleukin-6	IL6	3.38	3.95	1.28	1.82	3.48
Interleukin-8	IL8	2.25	2.83	1.28	−1.84	−1.25
Interleukin-9	IL-9	−1.39	−1.12	2.85	−1.06	−1.26
Interleukin-10	IL10	3.81	1.68	2.08	1.36	1.15
Interleukin-11	IL-11	1.02	−2.34	−1.50	−1.39	−1.80
Pro-interleukin-16	IL16	3.02	−1.45	−1.42	1.98	1.79
Interleukin-17A	IL-17A	1.74	2.74	1.35	2.56	1.39
Interleukin-17B	IL17B	13.90	3.20	2.94	2.07	7.54
Interleukin-17D	IL17D	2.91	11.47	3.16	−1.41	1.55
Interleukin-18BP	IL-18BP	−2.24	1.12	1.41	1.46	−1.74
Interleukin-17F	IL17F	−1.46	11.22	−1.55	−1.09	−1.13
Interleukin-19	IL19	2.09	2.51	1.03	2.05	−1.32
Interleukin-24	IL24	1.16	3.53	3.13	2.21	2.27
Interleukin-31	IL31	1.85	16.15	13.18	13.64	1.49
Interleukin-32	IL32	2.25	1.82	−1.07	1.59	1.29
Interleukin-33	IL33	2.87	2.23	1.19	1.30	−1.70
Interleukin-34	IL34	2.01	2.46	−1.07	2.39	−1.20
Interleukin-36α	IL36A	4.38	1.70	−1.23	1.13	−1.01
Interleukin-36β	IL36B	6.59	2.31	2.33	1.25	9.74
Interleukin-37	IL37	1.17	3.11	1.36	−1.06	1.13
Colony stimulating factor 2	CSF2	1.69	6.91	2.54	1.71	1.67
Fibroblast growth factor 2	FGF2	−3.02	2.57	−1.24	1.80	1.36
Fibroblast growth factor 5	FGF5	8.95	−1.22	−1.16	1.03	9.55
Fibroblast growth factor 6	FGF6	1.58	1.20	7.19	1.45	3.01
Fibroblast growth factor 9	FGF9	−1.34	3.59	−1.51	1.77	2.68
Fibroblast growth factor 14	FGF14	1.13	−1.08	1.08	−1.06	3.10
Fibroblast growth factor 18	FGF18	−1.24	13.76	1.68	−1.09	−1.86
Fibroblast growth factor 21	FGF21	1.74	−1.40	−1.30	6.29	1.47
Fibroblast growth factor 22	FGF22	3.02	3.03	−1.33	−1.37	1.47
Growth arrest-specific protein 1	GAS1	3.56	2.33	1.97	1.86	2.36
Growth arrest-specific protein 2	GAS2	−1.22	−1.14	−1.03	8.87	1.32
Growth/differentiation factor 11	GDF11	−1.04	3.04	1.68	1.21	1.04
Insulin-like growth factor I	IGF1	7.10	2.70	2.35	1.88	1.14
Insulin-like growth factor II	IGF2	2.45	7.87	−3.18	−3.43	−1.21
TGFβ	TGFB1	1.61	2.80	1.71	−1.35	−1.06
TNFα	TNFA	1.97	7.57	1.67	1.57	2.10